Research Progress of Raman Spectroscopy in the Diagnosis of Early Lung Cancer.
10.3779/j.issn.1009-3419.2018.07.10
- Author:
Xiaoru TIAN
1
;
Yi ZHANG
1
Author Information
1. Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
- Publication Type:Journal Article
- Keywords:
Early diagnosis;
Lung neoplasms;
Raman spectroscopy
- MeSH:
Early Detection of Cancer;
methods;
Humans;
Lung Neoplasms;
diagnosis;
Spectrum Analysis, Raman;
methods
- From:
Chinese Journal of Lung Cancer
2018;21(7):560-564
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer (LC) is the most common cancer and the leading cause of cancer-related death worldwide. The 5-year survival rate for LC remains low at 18% and is 5% for patients with metastatic disease, while the 5-year overall survival rate of patients with stage I NSCLC can reach 77.9%, hence early diagnosis and treatment of LC is the key to improve the prognosis. As a non-invasive detection technique, Raman spectroscopy can realize the non-destructive detection of the differences in molecular level structure between cancerous tissues and normal tissues, which can be used for the early diagnosis of lung cancer. The aim of this review is to summarize the progress of Raman spectroscopycombined with different tissue or body fluid samplesin the diagnosis of early LC.
.