Emerging Actions of Pterostilebene on Cancer Research.

Author: Xiaoyan ZHANG ¹ ; Jiao ZHANG ² ; Liqun XU ² ; Zhiqiang MA ² ; Shouyin DI ² ; Yuan GAO ² ; Xiaofei LI ² ; Xiaolong YAN ² ; Hongmei ZHANG ¹
Author Information

1. Department of Clinical Oncology, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China.
2. Department of Thoracic Surgery, Tangdu Hospital, the Fourth Military Medical University, Xi'an 710038, China.
Publication Type:Journal Article
Keywords: Apoptosis; Invasion; Neoplasms; Peterostilbene; Proliferation
MeSH: Animals; Antineoplastic Agents, Phytogenic; chemistry; pharmacology; Humans; Neoplasms; drug therapy; Plant Extracts; chemistry; pharmacology; Stilbenes; chemistry; pharmacology
From: Chinese Journal of Lung Cancer 2018;21(12):931-936
CountryChina
Language:Chinese
Abstract: Pterostilbene (3,5-dimethoxy-4'-hydroxystilbene) is a polyphenolic compound primarily found in blueberries, grapes, and a tree wood, pterocarpus marsupium. Studies demonstrate that pterostilbene inhibits a variety of cancers, such as lung, breast, stomach, colon, etc. The anti-cancer activities are related to the regulation of several hallmarks of cancer. Moreover, pterostilbene exhibits much greater bioavailability and bioactivity than resveratrol which warrants further investigation in the anti-cancer functions and mechanisms. .