The Clinical Efficacy of Nailfold Capillaroscopy in Rheumatic Diseases.
10.3904/kjm.2016.90.6.494
- Author:
Hyun Sook KIM
1
Author Information
1. Department of Internal medicine, The Soonchunhyang University College of Medicine, Seoul, Korea. healthyra@schmc.ac.kr
- Publication Type:Review
- Keywords:
Nailfold capillaroscopy;
Rheumatic diseases
- MeSH:
Arthritis, Rheumatoid;
Early Diagnosis;
Humans;
Lupus Erythematosus, Systemic;
Microscopic Angioscopy*;
Mixed Connective Tissue Disease;
Rheumatic Diseases*;
Scleroderma, Systemic;
Treatment Outcome*;
Ulcer
- From:Korean Journal of Medicine
2016;90(6):494-500
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nailfold capillaroscopy (NFC) is a non-invasive morphological study that routinely used to differentiate between a primary and secondary Raynaud's phenomenon (RP). Secondary RP is a manifestation of an underlying rheumatic disease that occurs in 80-95% of patients with systemic sclerosis (SSc), 75% of patients with mixed connective tissue disease and in 20-25% of patients with systemic lupus erythematosus or rheumatoid arthritis. These RP frequently precedes the underlying disease by many years. The well-established roles of NFC are the early diagnosis of SSc, and potential for predicting clinical complication, as like digital ulcers. The following review will present a technique about how to perform NFC and optimal assessment with emphasis on its possible role as a reliable diagnostic tool.
