Acute Kidney Injury due to Rbadomyolysis Complicated with Zolpidem Overdose.
10.3904/kjm.2016.90.6.550
- Author:
Hong Ik KIM
1
;
Seong Ho JO
;
Hyo Lim HONG
;
In Hee LEE
;
Ki Sung AHN
;
Gun Woo KANG
Author Information
1. Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea. gwkang4540@hanmail.net
- Publication Type:Case Report
- Keywords:
Zolpidem;
Acute kidney injury;
Rhabdomyolysis
- MeSH:
Acute Kidney Injury*;
Benzodiazepines;
Blood Urea Nitrogen;
Creatine Kinase;
Creatinine;
Dizziness;
Headache;
Humans;
Middle Aged;
Nausea;
Renal Dialysis;
Rhabdomyolysis;
Seoul;
Sleep Initiation and Maintenance Disorders;
Suicide
- From:Korean Journal of Medicine
2016;90(6):550-553
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Zolpidem (Stilnox®, Handok, Seoul, Korea) is a hypnotic imidazopyridine that is often used to treat insomnia because it has less abuse and addiction potential than benzodiazepines. Its side effects include headache, dizziness, and nausea, but these are mild. Zolpidem intoxication rarely has severe complications. Here, we report a case of acute kidney injury due to rhabdomyolysis related to zolpidem. A 51-year-old man was admitted with drowsy mentality after taking an overdose of zolpidem in a suicide attempt. Laboratory findings showed a blood urea nitrogen of 59.9 mg/dL, serum creatinine of 5.8 mg/dL, and creatine phosphokinase of 16,210 IU/L. Acute kidney injury associated with rhabdomyolysis complicating zolpidem intoxication was diagnosed. The patient was managed with hemodialysis and recovered completely in terms of renal function and muscle enzyme levels.
