Acquired Pure Red Cell Aplasia following Autoimmune Hemolytic Anemia in Systemic Lupus Erythematosus.
10.3904/kjm.2016.90.6.554
- Author:
Mi Hee KIM
1
;
Ji Yeon CHOI
;
Sang Min LEE
;
Seung Won AHN
;
Seung Min JUNG
;
Hyunjung KIM
;
Hye Sung WON
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. woncomet@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Red-cell aplasia, Pure;
Anemia, Hemolytic, Autoimmune;
Lupus erythematosus, Systemic
- MeSH:
Anemia;
Anemia, Hemolytic, Autoimmune*;
Anemia, Macrocytic;
Autoantibodies;
Bone Marrow;
Erythrocytes;
Humans;
Lupus Erythematosus, Systemic*;
Red-Cell Aplasia, Pure*;
Reticulocytosis
- From:Korean Journal of Medicine
2016;90(6):554-558
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pure red cell aplasia (PRCA) is a rare hematological disorder characterized by severe normochromic normocytic anemia and reticulocytopenia due to erythroid progenitor depletion in an otherwise normal bone marrow. Autoimmune hemolytic anemia (AIHA) is caused by autoantibodies directed against red blood cells with normocytic or macrocytic anemia with reticulocytosis. Both diseases can develop in conjunction with various underlying diseases, such as immunological disorders. Although rare, there have been a few cases of AIHA followed by PRCA. Here, we report a patient who developed PRCA following AIHA and was later diagnosed with systemic lupus erythematosus.
