Key technologies in digital breast tomosynthesis system:theory, design, and optimization.

Mingqiang LI; Kun MA; Xi Tao; Yongbo Wang; Ji HE; Ziquan Wei; Geofeng Chen; Sui LI; Dong Zeng; Zhaoying Bian; Guohui WU; Shan Liao; Jianhua MA

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Key technologies in digital breast tomosynthesis system:theory, design, and optimization.

Author: Mingqiang LI ¹ ; Kun MA ¹ ; Xi TAO ¹ ; Yongbo WANG ¹ ; Ji HE ¹ ; Ziquan WEI ¹ ; Geofeng CHEN ¹ ; Sui LI ¹ ; Dong ZENG ¹ ; Zhaoying BIAN ¹ ; Guohui WU ² ; Shan LIAO ² ; Jianhua MA ¹
Author Information

1. School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China.
2. Shenzhen Anke High Technology Co. Ltd., Shenzhen 518100, China.
Publication Type:Journal Article
Keywords: digital breast tomosynthesis; filtered back projection; geometric correction; image chain design and optimization; projection enhancement
MeSH: Algorithms; Artifacts; Breast; diagnostic imaging; Female; Humans; Mammography; methods; Phantoms, Imaging; Radiographic Image Enhancement; methods
From: Journal of Southern Medical University 2019;39(2):192-200
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To develop a digital breast tomosynthesis (DBT) imaging system with optimizes imaging chain.
METHODS:Based on 3D tomography and DBT imaging scanning, we analyzed the methods for projection data correction, geometric correction, projection enhancement, filter modulation, and image reconstruction, and established a hardware testing platform. In the experiment, the standard ACR phantom and high-resolution phantom were used to evaluate the system stability and noise level. The patient projection data of commercial equipment was used to test the effect of the imaging algorithm.
RESULTS:In the high-resolution phantom study, the line pairs were clear without confusing artifacts in the images reconstructed with the geometric correction parameters. In ACR phantom study, the calcified foci, cysts, and fibrous structures were more clearly defined in the reconstructed images after filtering and modulation. The patient data study showed a high contrast between tissues, and the lesions were more clearly displayed in the reconstructed image.
CONCLUSIONS:This DBT imaging system can be used for mammary tomography with an image quality comparable to that of commercial DBT systems to facilitate imaging diagnosis of breast diseases.