TBX20 - an important target gene for the prevention and treatment of cardiovascular diseases.
10.3760/cma.j.issn.1003-9406.2019.05.025
- Author:
Zhefu HU
1
;
Qizhu TANG
Author Information
1. Intensive Care Unit, Renmin Hospital of Wuhan University, Hubei 430060, China. Email: qztang@whu.edu.cn.
- Publication Type:Journal Article
- MeSH:
Cardiovascular Diseases;
prevention & control;
Gene Expression Regulation;
Humans;
T-Box Domain Proteins;
genetics
- From:
Chinese Journal of Medical Genetics
2019;36(5):513-515
- CountryChina
- Language:Chinese
-
Abstract:
The T-Box transcription factor family plays a crucial role during heart development. A large amount of clinical evidence showed TBX 1, 2, 5, 18, 20 proteins to be strongly associated with human congenital heart diseases including atrial septal defect, mitral valve disease, and tetralogy of Fallot. Among these, TBX20 has attracted much attention. This article gives a brief review for the progress made in the research on TBX20 and cardiovascular disease.
