Progress in endosomal Na⁺,K⁺/H⁺ antiporter in Arabidopsis thaliana.
- Author:
Liguang WANG
1
Author Information
- Publication Type:Journal Article
- Keywords: K⁺/H⁺ antipoporter; endosomal Na+; ion transport; protein storage; subcellular localization; vacuolar trafficking
- MeSH: Arabidopsis; Arabidopsis Proteins; Endosomes; Sodium-Hydrogen Exchangers; Vacuoles
- From: Chinese Journal of Biotechnology 2019;35(8):1424-1432
- CountryChina
- Language:Chinese
- Abstract: Important progress has been made in the interpretation of subcellular location, ion transport characteristics and biological functions of endosomal Na⁺,K⁺/H⁺ antiporter in Arabidopsis thaliana. The endosomal Na⁺,K⁺/H⁺ antiporter contain two members, AtNHX5 and AtNHX6, whose amino acid sequence similarity is 78.7%. Studies have shown that AtNHX5 and AtNHX6 are functionally redundant, and they are all located in Golgi, trans-Golgi network (TGN), endoplasmic reticulum (ER) and prevacuolar compartment (PVC). AtNHX5 and AtNHX6 are critical for salt tolerance stress and the homeostasis of pH and K⁺. It has been reported that there are conservative acidic amino acid residues that can regulate their ion activity in the endosomal NHXs transmembrane domain, which plays a decisive role in their own functions. The results of the latest research indicate that endosomal NHXs affect vacuolar transport and protein storage, and participate in the growth of auxin-mediated development in A. thaliana. In this paper, the progress of subcellular localization, ion transport, function and application of endosomal NHXs in A. thaliana was summarized.
