Progress in cerebrospinal fluid proteome technology and its clinical application.

Author: Linpeng YANG ¹ ; Pengcheng FAN ² ; Wanjun JIN ¹ ; Huiping MA ¹ ; Linlin JING ¹ ; Zhengping JIA ¹
Author Information

1. Key Laboratory of Prevention and Cure for the Plateau Environmental Damage of PLA, The 940th Hospital of PLA Joint Logistics Support Force, Lanzhou 730050, Gansu, China.
2. State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China.
Publication Type:Journal Article
Keywords: cerebrospinal fluid; clinical application; diagnostic markers; mass spectrometry; proteomics
MeSH: Biomarkers; Cerebrospinal Fluid Proteins; Proteome; Proteomics
From: Chinese Journal of Biotechnology 2019;35(9):1643-1649
CountryChina
Language:Chinese
Abstract: Cerebrospinal fluid surrounds and supports the central nervous system, including the ventricles and subarachnoid spaces. Cerebrospinal fluid should be an important source of biomarkers for central nervous system diseases because it is in direct contact with the central nervous system. Many studies are reported on cerebrospinal fluid proteomics, highlighting many recent progresses. Here, we review recent advances in proteomics technology and clinical application of cerebrospinal fluid.