- Author:
Jian DING
1
;
Hongzhen LUO
2
;
Zhongping SHI
1
Author Information
- Publication Type:Journal Article
- Keywords: butanol fermentation; cell self-adaption; environmental variations; fermentation optimization; heterologous proteins production
- MeSH: Adaptation, Physiological; Butanols; metabolism; Environment; Fermentation; Pichia; cytology; metabolism
- From: Chinese Journal of Biotechnology 2019;35(10):1986-2002
- CountryChina
- Language:Chinese
- Abstract: In industrial fermentation processes, bacteria have to adapt environmental stresses. Sometimes, such a self-adaption does not work and will cause fermentation failures, although such adaptation also can generate unexpected positive effects with improved fermentation performance. Our review introduces cell self-adaption to environmental variations or stress, process optimization based on such self-adaptions, with heterologous proteins production by Pichia pastoris and butanol fermentation as examples. Our review can sever as reference for fermentation optimization based on cell self-adaption.