Progress in intelligent control of industrial bioprocess.
- Author:
Xiwei TIAN
1
;
Guan WANG
1
;
Siliang ZHANG
1
;
Yingping ZHUANG
1
Author Information
- Publication Type:Journal Article
- Keywords: industrial bioprocess; intelligent control; on-line sensing technology; physiological metabolism; process big data
- MeSH: Bioreactors; Biotechnology; Fermentation; Industrial Microbiology
- From: Chinese Journal of Biotechnology 2019;35(10):2014-2024
- CountryChina
- Language:Chinese
- Abstract: Industrial bioprocess is a complex systematic process and bio-manufacturing can be realized on the basis of understanding the metabolism process of living cells. In this article, the multi-scale optimization principle and practice of industrial fermentation process are reviewed, including multi-scale optimizing theory and equipment, on-line sensing technology for cellular macroscopic metabolism, and correlated analysis of physiological parameters. Furthermore, intelligent control of industrial bioprocess is further addressed, in terms of new sensing technology for intracellular physiological metabolism, big database establishment and data depth calculation, intelligent decision.
