Chemical constituents from lipophilic parts of stems of Celastrus monospermus.
10.19540/j.cnki.cjcmm.20171027.015
- Author:
Ming-Xiang CHEN
1
;
Xue-Mei YANG
1
;
Ze-Chun LIAO
1
;
Hong-Yu ZHENG
1
;
Li-Qiao HUANG
1
;
Ming-Bin ZHENG
1
Author Information
1. School of Pharmacy, Guangdong Medical University, Dongguan 523808, China.
- Publication Type:Journal Article
- Keywords:
Celastrus monospermus;
chemical constituents;
friedelane;
stems
- MeSH:
Celastrus;
chemistry;
Phytochemicals;
isolation & purification;
Plant Stems;
chemistry;
Triterpenes;
isolation & purification
- From:
China Journal of Chinese Materia Medica
2018;43(2):336-344
- CountryChina
- Language:Chinese
-
Abstract:
The chemical constituents from lipophilic parts of the stems of Celastrus monospermus were studied in this paper. The compounds were separated and purified by repeated column chromatographic methods including silica gel, ODS and Sephadex LH-20, and the structures of compounds were determined by spectral data analyses. Twenty six compounds were obtained and identified as 3-oxofriedelane(1), 3-oxofriedelan-28-al(2), 3,12-dioxofriedelane(3), 3β-hydroxyolean-12-en(4), 3-oxo-28-hydroxyfriedelane(5), 3-oxo-29-hydroxyfriedelane(6), 3-oxo-11β-hydroxyfriedel-ane(7), 3-oxo-16α-hydroxyfriedelane(8), 3,12-dioxo-28-hydroxyfriedelane(9), 1,3-dioxo-15α-hydroxyfriedelane(10), 3β,6α-dihydroxyolean-12-en(11), 3-oxo-7α,26-dihydroxyfriedel-ane(12), oleanolic acid(13), 3,15-dioxofriedelane(14), 3α-friedelinol(15), 3,12-dioxofriedelan-28-al(16), 3-oxo-12α-hydroxyfriedelane(17), 3,15-dioxo-12α-hydroxyfriedelane(18), 3β,11β-dihydroxyolean-12-en(19), 1β,3β-dihydroxylupan-20(29)-en(20), 3-oxo-12α,28-dihydroxyfriedelane(21), 3β,23-epoxyfriedelan-28-oic acid(22), salaquinone A(23), 2α,3β-dihydroxyfriedelan-28-oic acid(24), 23-nor-6-oxodemethylpristimerol(25) and 3-oxo-friedelan-27,28-dioic acid(26). Among them, compounds 8, 10-15, 18-20, 22-26 were obtained from this plant for the first time, and compounds 8, 10, 12, 14-15, 18, 22-24, 26 were separated from the genus Celastrus for the first time.
