Evidence-based evaluation on safety of Tripterygium wilfordii preparations.
10.19540/j.cnki.cjcmm.2018.0010
- Author:
Xue FENG
1
;
Sai-Nan FANG
1
;
Yu-Xin GAO
2
;
Jian-Ping LIU
1
;
Wei CHEN
1
Author Information
1. Centre for Evidence-Based Chinese Medicine， Beijing University of Chinese Medicine， Beijing 100029， China.
2. Department of Sociology， Acadia University， Wolfville B4P2R6， Canada.
- Publication Type:Journal Article
- Keywords:
Tripterygium wilfordii;
evidence-based evalutation;
safety
- MeSH:
Bibliometrics;
Drugs, Chinese Herbal;
standards;
Tripterygium
- From:
China Journal of Chinese Materia Medica
2018;43(3):425-439
- CountryChina
- Language:Chinese
-
Abstract:
The study was aimed to conduct an evidence-based evaluation on the safety of Tripterygium wilfordii(TW) preparations through a method combined bibliometrics research with evidence-based evaluation research， to provide evidence-based safety information of the TW preparations(nephrotoxicity) for the government decision-making and clinical application， and to provides methods and suggestions for evaluating nephrotoxicity of Chinese herbal medicine(CHM) in the future. We searched relevant databases at home and abroad systematically， and six Chinese and English databases including CNKI， SinoMed， VIP， WanFang， PubMed， and Cochrane library were comprehensively searched. All types of research documents about the safety of TW preparations. Literature were screened and extracted based on inclusion and exclusion criteria. The methodology quality of all included studies were assessed by internationally recognized evaluation tools or standards. The incidence rate was analyzed by using R software. Subgroup analysis were conducted according to the type of disease treated， drug delivery way， medication time， and study types.
