Advance in studies on pharmacokinetics of baicalin.
10.19540/j.cnki.cjcmm.20171106.011
- Author:
Hong-Chao ZHOU
1
;
Rui DU
2
;
Hui WANG
1
;
Fan-Li ZENG
1
;
Kun SHI
1
;
Jian-Ming LI
1
;
Ying ZONG
1
Author Information
1. College of Chinese Medicine Materials, Jilin Agricultural University, Changchun 130118, China.
2. Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education of the People's Republic of China, Laboratory of Production and Product Application of Sika Deer of Jilin Province, Changchun 130118, China.
- Publication Type:Journal Article
- Keywords:
baicalin;
bioavailability;
pharmacokinetics;
traditional Chinese medicine
- MeSH:
Drugs, Chinese Herbal;
pharmacokinetics;
Flavonoids;
pharmacokinetics;
Scutellaria baicalensis
- From:
China Journal of Chinese Materia Medica
2018;43(4):684-688
- CountryChina
- Language:Chinese
-
Abstract:
Scutellariae baicalensis is one of the most important traditional Chinese medicinal herbs, mainly distributed in Shandong and Hebei provinces. It has significant pharmacological effects such as antimicrobial activity, anti-inflammatory and antioxidation. Baicalin is one of its main effective components. However, baicalin's low bioavailability has restricted its clinical application. In recent decades, extensive studies have been carried out on the metabolism of baicalin at home and abroad. In order to provide scientific references for baicalin's further studies, this paper would not only review the advances in pharmacokinetics research of baicalin and Chinese herbal preparations containing baicalin, but also make a summary on research status of baicalin.
