Recent advances in analysis of endogenous toxic components in traditional Chinese medicines.
10.19540/j.cnki.cjcmm.20180703.009
- Author:
Ya-Ping DUAN
1
;
Jiao-Yang LUO
1
;
Hao LIU
1
;
Li-Nan SHAN
1
;
Shi-Hai YANG
2
;
Mei-Hua YANG
1
Author Information
1. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
2. College of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118, China.
- Publication Type:Journal Article
- Keywords:
analytic methods;
endogenous toxic components;
evaluation criteria;
grading;
traditional Chinese medicine
- MeSH:
Drugs, Chinese Herbal;
Medicine, Chinese Traditional
- From:
China Journal of Chinese Materia Medica
2018;43(24):4808-4816
- CountryChina
- Language:Chinese
-
Abstract:
Endogenous toxic components have become an important topic in the field of traditional Chinese medicines (TCMs). Since the endogenous toxic components in TCMs are often used as clinical effective components, the safety and effectiveness of endogenous toxic substances has become an important part of the research of TCMs. In this paper, the classification and evaluation criteria of toxic Chinese medicinal materials are described, and the analytical methods of endogenous components in TCMs are summarized and expounded base on with the techniques of chromatography, spectroscopy, immunoassay, and so on. On this basis, the problems in terms of endogenous toxic components are analyzed and discussed. This paper could provide ideas and methods for the evaluation of the validity and safety of TCMs containing endogenous toxic components.
