Research advancement in natural anti-cancer product.
- Author:
Jie YIN
1
;
Qi LI
2
;
Li-Dong SUN
2
;
Qing YANG
2
;
Zheng ZHAO
2
;
Qing-Sen RAN
2
;
Xiao-Gang WENG
2
;
Ying CHEN
2
;
Ya-Jie WANG
2
;
Yu-Jie LI
2
;
Wei-Yan CAI
2
;
Xiao-Xin ZHU
2
Author Information
- Publication Type:Journal Article
- Keywords: innovative drug target; natural products; research and development of anticancer drugs
- MeSH: Antineoplastic Agents; pharmacology; Biological Products; pharmacology; Humans; Neoplasms; drug therapy; Research
- From: China Journal of Chinese Materia Medica 2019;44(1):19-27
- CountryChina
- Language:Chinese
- Abstract: Human health has been severely threatened by malignant tumors continuously.Rational and effective drug use provides an effective means for the treatment of malignant tumors,and is expected to become an important way to solve the problem of tumor treatment in the future.In recent years,with the escalation of new cancer theories and the emergence of clinical drug resistance,innovative research and development of anti-cancer drugs has always been a hot spot and focus in cancer research.Among them,the discovery of novel anti-cancer drugs from natural compound is of top priority due to its strong anti-cancer efficacy and the abundant drug resources.Therefore,it is imperative to systematically summarize the cutting-edge advancements of the natural products and their potential pharmacological mechanisms according to the characteristics of tumor progression,and put forward the new directions and trends for further development of anti-cancer natural products in the future.Specifically,the research advancements on anti-cancer effect of natural products were reviewed,focusing on both the traditional and innovative application.We hope this review could bring the light on the research path of the natural anti-cancer products clearly and comprehensively,and also provide inspirations for innovative,safer and more effective anti-cancer drug development and exploration.
