Application of affinity chromatography and its mathematical model in study of active components of traditional Chinese medicine.
10.19540/j.cnki.cjcmm.20181101.015
- Author:
Yu-Chu CHEN
1
;
Lu ZHAO
1
;
Xi-Ming XU
1
;
Jiang-Nan YU
1
;
Shan-Shan TONG
1
Author Information
1. School of Pharmacy,Jiangsu University Zhenjiang 212013,China.
- Publication Type:Journal Article
- Keywords:
adsorption isotherm model;
adsorption thermodynamics;
affinity chromatography;
kinetic model;
traditional Chinese medicine
- MeSH:
Adsorption;
Chromatography, Affinity;
Drugs, Chinese Herbal;
chemistry;
Medicine, Chinese Traditional;
Models, Theoretical
- From:
China Journal of Chinese Materia Medica
2019;44(1):40-47
- CountryChina
- Language:Chinese
-
Abstract:
Affinity chromatography is characterized by its high specificity,high recovery rate and sensitivity,and it has been widely used in the selection of active ingredients of traditional Chinese medicine,separation and enrichment of low molecular weight sugars and protein peptides,research on mechanism of action and discovery of targets.This paper reviewed the application of affinity chromatography and its adsorption isotherm model,kinetic model and adsorption thermodynamic mechanism in the field of traditional Chinese medicine.This summarizes and provides thinking for comprehensive applications of affinity chromatography theory in the field of active ingredient screening,purification and medicine interaction.
