Regularity of traditional Chinese medicine prescriptions for same treatment for cardiovascular and cerebrovascular diseases.
10.19540/j.cnki.cjcmm.20181101.007
- Author:
Jia-Ming GAO
1
;
Ming LYU
1
;
Wei-Wei XIE
1
;
Xin-Yan LIU
1
;
Bu-Chang ZHAO
2
;
Yan ZHU
1
Author Information
1. Tianjin State Key Laboratory of Modern Chinese Medicine,Tianjin University of Traditional Chinese Medicine Tianjin 300193,China Research and Development Center of Traditional Chinese Medicine,Tianjin International Joint Academy of Biotechnology & Medicine Tianjin 300457,China.
2. Tianjin State Key Laboratory of Modern Chinese Medicine,Tianjin University of Traditional Chinese Medicine Tianjin 300193,China Shangdong Buchang Pharmaceuticals Co.,Ltd. Heze 274000,China.
- Publication Type:Journal Article
- Keywords:
Chinese medicine prescription regularity;
cardio-cerebral vascular disease cotreatment;
traditional Chinese medicine inheritance system
- MeSH:
Cardiovascular Diseases;
drug therapy;
Cerebrovascular Disorders;
drug therapy;
Data Mining;
Drugs, Chinese Herbal;
therapeutic use;
Humans;
Medicine, Chinese Traditional;
Prescriptions
- From:
China Journal of Chinese Materia Medica
2019;44(1):193-198
- CountryChina
- Language:Chinese
-
Abstract:
To explore the regularity of traditional Chinese medicine(TCM) prescriptions for cardio-cerebrovascular diseases,the core drug groups with common therapeutic effects on cerebrovascular diseases represented by stroke and cardiovascular diseases represented by coronary artery disease were extracted,and their consistency and difference in the treatment of different diseases were analyzed.A total of 388 Chinese patent medicines were collected for the treatment of cerebrovascular diseases,cardiovascular diseases and cardio-cerebrovascular diseases.The dominant and recessive patterns of Chinese patent medicines in clinical use were found by "frequency analysis","compatibility analysis" and "network analysis" respectively.According to the findings of the three parts,Salviae Miltiorrhizae Radix et Rhizoma,Chuanxiong Rhizoma,Carthami Flos and Astragali Radix have a high frequency of use in the treatment of brain disease,heart disease and both,with frequent combined medication.Data mining confirmed the core drug combinations for the treatment of cerebral and cardiac vascular diseases,so as to reveal the similarities and differences in the drug use of Chinese medicine for these diseases,and provide a basis for the rational use of traditional Chinese medicine in clinical practice.This analysis also defines a new direction for the future development of prescription combinations for different indications of cerebral and cardiac diseases.