Prevention, control and vaccine development of African swine fever: challenges and countermeasures.

Tao Wang; Yuan Sun; Yuzi Luo; Hua-ji Qiu

Return

Prevention, control and vaccine development of African swine fever: challenges and countermeasures.

Author: Tao WANG ¹ ; Yuan SUN ¹ ; Yuzi LUO ¹ ; Hua-Ji QIU ¹
Author Information

1. Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, Heilongjiang, China.
Publication Type:Journal Article
Keywords: African swine fever; African swine fever virus; preventive measures; vaccines
MeSH: African Swine Fever; African Swine Fever Virus; Animals; Biomedical Research; China; Disease Outbreaks; Swine; Vaccines
From: Chinese Journal of Biotechnology 2018;34(12):1931-1942
CountryChina
Language:Chinese
Abstract: African swine fever (ASF) is a hemorrhagic and devastating infectious disease of pigs caused by African swine fever virus (ASFV), with mortality up to 100%. The first ASF outbreak occurred in China in August 2018, followed by 69 cases of ASF in 18 provinces in more than three months, causing a heavy burden to the pig industry. Based on the global epidemic situation of ASF and the experience of prevention and control in other countries, the ASF control and eradication situation in China is extremely complex and serious. The availability of effective and safe ASF vaccines is an urgent requirement to reinforce control and eradication strategies. Therefore, this article starts with the latest findings of ASFV, summarizes the progress in prevention and control strategies and vaccine approaches for ASFV. We also discuss the challenges of preventing and controlling ASF, focusing on current vaccine strategies, the gaps, future research directions, and key scientific issues in commercial applications. We hope to provide basic information for the development of vaccines and prevention control strategies against this disease in China.