Clozapine Induced Neuroleptic Malignant Syndrome

Author: Yong Suk JO ¹ ; Hyung Ah JO ; Byung Chul YU ; Jung Hoon SHIN ; Kook Hwan OH
Author Information

1. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Publication Type:Case Report
Keywords: acute kidney injury; clozapine; neuroleptic malignant syndrome; rhabdomyolysis
MeSH: Acute Kidney Injury; Antipsychotic Agents; Clozapine; Female; Humans; Middle Aged; Neuroleptic Malignant Syndrome; Pulmonary Edema; Renal Dialysis; Respiration, Artificial; Rhabdomyolysis
From:The Korean Journal of Critical Care Medicine 2017;32(3):291-294
CountryRepublic of Korea
Language:English
Abstract: Neuroleptic malignant syndrome is a rare, but potentially life-threatening adverse event associated with the use of neuroleptic agents. We describe the case of a 47-year-old schizophrenic woman who was treated with clozapine for years. The patient developed acute renal failure with pulmonary edema, and underwent mechanical ventilation and hemodialysis.