Fatal Tumor Lysis Syndrome During Chemotherapy in Small Cell Lung Cancer.
10.4046/trd.2008.64.3.215
- Author:
Eun Hee KOOK
1
;
Min Soo KIM
;
Se Han AHN
;
Se Young JEON
;
Jung Ho YOON
;
Min Sung HAN
;
Cheol Hyeon KIM
;
Jae Cheol LEE
Author Information
1. Department of Internal Medicine, Korea Cancer Center Hospital, Seoul, Korea. jclee@kcch.re.kr
- Publication Type:Case Report
- Keywords:
Small cell lung cancer;
Tumor lysis syndrome
- MeSH:
Humans;
Incidence;
Leukemia;
Lymphoma, Non-Hodgkin;
Small Cell Lung Carcinoma;
Tumor Lysis Syndrome
- From:Tuberculosis and Respiratory Diseases
2008;64(3):215-218
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tumor lysis syndrome is a life-threatening complication of anti-cancer therapy that typically occurs in patients with large, rapidly growing and treatment-sensitive tumors such as high-grade lymphomas and acute leukemias. However, its incidence in solid tumors has been known to be very low. Tumor lysis syndrome in solid tumors has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of fatal tumor lysis syndrome developed during chemotherapy in extensive-stage small cell lung cancer, along with a brief review of the relevant literature considering the rarity of this manifestation in solid tumor.
