Primary Invasive Intestinal Aspergillosis in a Non-Severely Immunocompromised Patient
10.4266/kjccm.2016.31.2.129
- Author:
Eunmi GIL
1
;
Tae Sun HA
;
Gee Young SUH
;
Chi Ryang CHUNG
;
Chi Min PARK
Author Information
1. Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. dr99.park@samsung.com
- Publication Type:Case Report
- Keywords:
critical illness;
gastrointestinal disease;
aspergillosis
- MeSH:
Acquired Immunodeficiency Syndrome;
Adrenal Cortex Hormones;
Aspergillosis;
Critical Illness;
Diagnosis;
Drug Therapy;
Gastrointestinal Diseases;
Humans;
Immune System Diseases;
Immunocompromised Host;
Intensive Care Units;
Male;
Middle Aged;
Neutropenia;
Respiratory System;
Risk Factors;
Shock, Septic
- From:The Korean Journal of Critical Care Medicine
2016;31(2):129-133
- CountryRepublic of Korea
- Language:English
-
Abstract:
Invasive aspergillosis (IA) is most commonly seen in patients with risk factors, such as cytotoxic chemotherapy, prolonged neutropenia, corticosteroids, transplantation and acquired immune deficiency syndrome. IA commonly occurs in the respiratory tract. Extrapulmonary aspergillosis is usually a part of a disseminated infection, and primary invasive intestinal aspergillosis is very rare. Herein, we report a case of an immunocompetent 53-year-old male who suffered recurrent septic shock in the intensive care unit (ICU) and was finally diagnosed as invasive intestinal aspergillosis without dissemination. IA is rarely considered for patients who do not have an immune disorder. Thus, when such cases do occur, the diagnosis is delayed and the clinical outcome is often poor. However, there is a growing literature reporting IA cases in patients without an immune disorder, mostly among ICU patients. Primary intestinal aspergillosis should be considered for critically ill patients, especially with severe disrupted gastrointestinal mucosal barrier.
