Polymyxin B Hemoperfusion in Pneumonic Septic Shock Caused by Gram-Negative Bacteria
10.4266/kjccm.2015.30.3.171
- Author:
Jung Wan YOO
1
;
Su Yeon PARK
;
Jin JEON
;
Jin Won HUH
;
Chae Man LIM
;
Younsuck KOH
;
Sang Bum HONG
Author Information
1. Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sbhong@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
endotoxin;
hemoperfusion;
polymyxin B;
shock, septic
- MeSH:
Cause of Death;
Critical Illness;
Gram-Negative Bacteria;
Hemoperfusion;
Humans;
Middle Aged;
Polymyxin B;
Polymyxins;
Pseudomonas aeruginosa;
Sepsis;
Shock, Septic
- From:The Korean Journal of Critical Care Medicine
2015;30(3):171-175
- CountryRepublic of Korea
- Language:English
-
Abstract:
Severe sepsis and septic shock are the main causes of death in critically ill patients. Early detection and appropriate treatment according to guidelines are crucial for achieving favorable outcomes. Endotoxin is considered to be a main element in the pathogenic induction of gram-negative bacterial sepsis. Polymyxin B hemoperfusion can remove endotoxin and is reported to improve clinical outcomes in patients with intra-abdominal septic shock, but its clinical efficacy for pneumonic septic shock remains unclear. Here, we report a case of a 51-year-old man with pneumonic septic shock caused by Pseudomonas aeruginosa, who recovered through polymyxin B hemoperfusion.
