Kawasaki Disease with Acute Respiratory Distress Syndrome after Intravenous Immunoglobulin Infusion
10.4266/kjccm.2014.29.4.336
- Author:
Yu Hyeon CHOI
1
;
Bong Jin LEE
;
June Dong PARK
;
Seung Hyo KIM
Author Information
1. Department of Pediatrics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
immunoglobulin;
mucocutaneous lymph node syndrome;
respiratory distress syndrome, adult
- MeSH:
Acute Kidney Injury;
Anemia, Hemolytic;
Aspirin;
Diagnosis;
Exanthema;
Fever;
High-Frequency Ventilation;
Humans;
Hypotension;
Immunoglobulins;
Immunoglobulins, Intravenous;
Lung;
Meningitis, Aseptic;
Mucocutaneous Lymph Node Syndrome;
Nitric Oxide;
Recurrence;
Respiratory Distress Syndrome, Adult;
Systemic Vasculitis
- From:The Korean Journal of Critical Care Medicine
2014;29(4):336-340
- CountryRepublic of Korea
- Language:English
-
Abstract:
Kawasaki disease (KD) is an acute systemic vasculitis of unknown etiology. We report a case of KD with acute respiratory distress syndrome (ARDS) after intravenous immunoglobulin (IVIG) infusion. Lung manifestations associated with KD have previously been reported in the literature. Although IVIG infusion is an effective therapy for acute KD, there are some reported complications related to IVIG infusion: hypotension, aseptic meningitis, acute renal failure, hemolytic anemia, etc. The case of KD reported here was treated with IVIG and aspirin. A few days after recovery from KD, the patient developed fever and maculopapular rash. A diagnosis of relapse KD was made and retreated with IVIG infusion. However, the patient developed ARDS four days after the second IVIG infusion. The patient recovered from ARDS after nine days of ICU care, which included high frequency oscillation ventilation with inhaled nitric oxide, steroid treatment and other supportive care.
