Dose-Volume Analysis of Lung and Heart according to Respiration in Breast Cancer Patients Treated with Breast Conserving Surgery.
10.4048/jbc.2012.15.1.105
- Author:
Jae Goo SHIM
1
;
Jeong Koo KIM
;
Won PARK
;
Jeong Min SEO
;
Chae Sun HONG
;
Ki Won SONG
;
Cheong Hwan LIM
;
Hong Ryang JUNG
;
Chan Hyeong KIM
Author Information
1. Department of Radiological Science, Hanseo University, Seosan, Korea. jkkim@hanseo.ac.kr
- Publication Type:Original Article
- Keywords:
Breast neoplasms;
Heart;
Lung;
Radiotherapy
- MeSH:
Breast;
Breast Neoplasms;
Cardiac Volume;
Female;
Heart;
Humans;
Lung;
Mastectomy, Segmental;
Radiotherapy, Adjuvant;
Respiration
- From:Journal of Breast Cancer
2012;15(1):105-110
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Adjuvant radiotherapy of breast cancer using a photon tangential field incurs a risk of late heart and lung toxicity. The use of free breathing (FB), expiration breath hold (EBH), and deep inspiration breath hold (DIBH) during tangential breast radiotherapy as a means of reducing irradiated lung and heart volume was evaluated. METHODS: In 10 women with left-sided breast cancer (mean age, 44 years) post-operative computed tomography (CT) scanning was done under different respiratory conditions using FB, EBH, and DIBH in 3 CT scans. For each scan, an optimized radiotherapy plan was designed with 6 MV photon tangential fields encompassing the clinical target volume after breast-conserving surgery. RESULTS: The results of dose-volume histograms were compared using three breathing pattern techniques for the irradiated volume and dose to the heart. A significant reduction dose to the irradiated heart volume for the DIBH breathing technique was compared to FB and EBH breathing techniques (p<0.05). CONCLUSION: This study demonstrated that the irradiated heart volume can be significantly reduced in patients with left-sided breast cancer using the DIBH breathing technique for tangential radiotherapy.
