Radiological findings of the estragonadal endodermal sinus tumors in children
10.3348/jkrs.1985.21.3.517
- Author:
Kounn Sik SONG
;
Kyung Mo YEON
- Publication Type:Original Article
- MeSH:
Angiography;
Animals;
Child;
Diagnosis;
Drug Therapy;
Endoderm;
Endodermal Sinus Tumor;
Female;
Gonads;
Humans;
Liver;
Lymph Nodes;
Male;
Necrosis;
Neoplasm Metastasis;
Neoplasms, Germ Cell and Embryonal;
Pelvis;
Placenta;
Rats;
Recurrence;
Retrospective Studies;
Sacrococcygeal Region
- From:Journal of the Korean Radiological Society
1985;21(3):517-523
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Endodernal sinus tumors(EST) are generally recognized as a germ cell tumors with extraembryonicdifferentiation that resemble the endodermal sinus of the rat placenta. Like other germ cell tumors the primaryEST may either occur in the gonads or in specific extragonadal sites. CT is the most accurate study in delineatingthe extent of primary and metastatic lesions particularly in the pelvis. Recently authors experienced six cases ofthe pathologically proven extragonadal endodermal sinus tumors in children and retrospectively analyzed theradiological findings including the CT. The results were as follows: 1 Of the 6 cases of extragonadal EST, theprimary lesion presented in the sacrococcygeal region in 5 patients and liver in one patient. 2. There were 4females and 2 males. Of the sacrococcygeal lesions 3 were females and 2 were males. 3. The age of presentationranged from 9 months to 3 years of age(mean age=21 months) 4. Conventional radiographic study of thesacrococcygeal lesion showed presacral, retrorectal soft tissue mass without calcification which extended into thebuttock. CT revealed well circumscribed enhancing soft tissue mass with irregular central low density areas. 5.Primay EST of the liver revealed ill-defined inhomogeneous mixed echogenic mass( ultrasound) and ill-defined lowdensity mass(CT). Angiography showed hypervascular mass with areas of necrosis and no evidence portal veininvasion. A-V shunting was not present. 6. Reginal lymph node metastasis was present at the time of diagnosis in 2cases of sacrococcygeal EST. 7. Local recurrence of tumor was noted in 2 patients with sacrococcygeal lesion aftersurgery and chemotherapy.
