Fibrous dysplasia of bone
10.3348/jkrs.1983.19.4.897
- Author:
Kyung Soo KIM
;
Sang Wook LEE
;
Young Jun CHO
;
Young Sook KIM
- Publication Type:Original Article
- MeSH:
Age Distribution;
Alkaline Phosphatase;
Congenital Abnormalities;
Diagnosis;
Extremities;
Female;
Femur;
Fibrous Dysplasia of Bone;
Fibrous Dysplasia, Polyostotic;
Fractures, Spontaneous;
Gwangju;
Humans;
Incidence;
Male;
Maxilla;
Nasal Obstruction;
Pelvis;
Ribs;
Serum
- From:Journal of the Korean Radiological Society
1983;19(4):897-907
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Fibrous dysplasia of bone is a skeletal developmental anomaly of unknown etiology characterized by single ormultiple areas of fibrous tissue replacement of medullary cavity of one or more bones. The disease may belocalized to single bone (monostotic form), of may affect multiple bone(polyostotic form). Eighteen cases offibrous dysplasia diagnosed by roentgenologic or histologic assessments at Chosum University Hospital ChonnamUniversity hospital and kwangju Christian Hospital during recent ten years were analyzed clinically andradiologically. The results were as follows; 1. 16 cases of them had monostotic involvement, and 2 cases showedpolyostotic disease, but none of our series presented Albright's syndrome. 2. The male to female ratio in thisseries was 10:8, but then 2 polyostotic forms of them were femals. In age distribution, peak incidence at the timeof diagnosis was in the age group of second decade (10 cases). 3. Maxilla (6 cases ) and femur (4 cases) werefrequently involved sites in patients with monostotic lesion, whereas polyostotic lesions diffusely affectedskull, pelvis, ribs and limb bones. 4. The clinical symptoms according to the extent and site of disease were veryvariable, which were localized painless or painful swelling, nasal obstruction, deformity of face or extremity andincidentally during routine roentgen study. 5. The chemical abnormality of blood serum was moderate degree ofelevated serum alkaline phosphatase in only one patients with monostotic lesion. 6. The main radiologic findingsof fibrous dysplasia were relatively well circumscribed single or multiloculated cystlike appearance, boneexpansion, cortical thinning and/or erosion, bony deformity and pathologic fracture, but especially in maxilla,dense homogenous area with expanding lesion was observed in our series.
