An experimental study on radionuclide imaging of bowel infarction using (99m)Tc-pyrophosphate
10.3348/jkrs.1981.17.1.149
- Author:
Sang Hoon BAE
;
Man Chung HAN
;
Bo Yeon CHO
;
Chang Soon KOH
- Publication Type:Original Article
- MeSH:
Infarction;
Intussusception;
Rabbits;
Radionuclide Imaging;
Technetium Tc 99m Pyrophosphate
- From:Journal of the Korean Radiological Society
1981;17(1):149-156
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
99m Tc-pyrophosphate was investigated for use as an indicator of intestinal infarction in intussusceptedbowel. Irreducible intussusceptions were created in 18 rabbits by surgery. 99mTc-pyrophosphate was then injectedintravenously 6-12, 18, 24 and 30-40 hours later for external scanning. In 15 of the rabbits, infaractiondeveloped with intussusception, and 13 of them demonstrated increased uptake of 99m Tc-pyrophosphate on externalinvivo scintiscans. The remained 2 of them showed no evidence of increased uptake. So false negative cases were2(sensitivity 86.7%). The 3 rabbits without infarction showed no increased uptake of radionuclide. Specimenscanning confirmed increased uptake of radionuclide in the infarcted segments. These observations suggest that 99mTc-pyrophosphate is a reliable indicator of the intestinal infarction that sometimes occures with intestinal intussusception.
