Diagnostic Accuracy of Imaging Study and the Impact of Clinical Risk Factors on the Presence of Residual Tumor Following Unplanned Excision of Soft Tissue Sarcomas
10.4055/jkoa.2019.54.2.150
- Author:
Eunsun OH
1
;
Sung Wook SEO
;
Jeonghwan JEONG
Author Information
1. Department of Orthopedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sungwseo@skku.edu
- Publication Type:Original Article
- Keywords:
sarcoma;
soft tissue;
unplanned excision;
neoplasm;
residual;
re-excision
- MeSH:
Diagnosis;
Humans;
Logistic Models;
Magnetic Resonance Imaging;
Neoplasm, Residual;
Positron-Emission Tomography;
Reoperation;
Risk Factors;
Sarcoma
- From:The Journal of the Korean Orthopaedic Association
2019;54(2):150-156
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study examined the diagnostic accuracy of an imaging study to find the factors that affect the presence of residual tumors after an unplanned excision of sarcomas. MATERIALS AND METHODS: Ninety-eight patients, who underwent a re-excision after unplanned surgery between January 2008 and December 2014, were enrolled in this study. Magnetic resonance imaging (MRI) was performed before reoperation in all patients. Positron emission tomography (PET)-computed tomography was performed on 54 patients. A wide re-excision and histology diagnosis were performed in all cases. The clinical variables were evaluated using univariate logistic regression and multivariate logistic regression. RESULTS: The presence of a deep-seated tumor increases the risk of remnant tumors (odds ratio: 3.21, p=0.02, 95% confidence interval: 1.25–8.30). The sensitivity for detecting residual tumors is high in MRI (sensitivity 0.79). CONCLUSION: Deep-seated tumors have a significantly higher risk of remnant tumors. Because the negative predictive value of MRI and PET scans is very low, reoperation should be performed regardless of a negative result.
