Late-Onset Candida Vertebral Osteomyelitis in Two Young Patients Who Underwent Heart Transplant Surgery
10.4055/jkoa.2019.54.1.72
- Author:
Min Seok KANG
1
;
In Seok SON
;
Tae Hoon KIM
;
Suk Ha LEE
Author Information
1. Department of Orthopedic Surgery, Seoul Red Cross Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Candida vertebral osteomyelitis;
opportunistic infection;
late-onset;
heart transplantation
- MeSH:
Candida;
Candidiasis;
Diagnosis;
Diagnosis, Differential;
Discitis;
Drug Therapy;
Heart Transplantation;
Heart;
Humans;
Opportunistic Infections;
Osteomyelitis;
Population Characteristics;
Rare Diseases
- From:The Journal of the Korean Orthopaedic Association
2019;54(1):72-77
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Candida vertebral osteomyelitis (CVO) is a rare disease that is a complication of intravenous drug use, but recently it has been recognized as mostly an opportunistic infection. Because CVO appears to mimic pyogenic spondylodiscitis in terms of the clinical and radiologic presentations, it is often neglected in a usual clinical setting. The clinical, radiological, and biological characteristics of CVO are often used to make a differential diagnosis with vertebral osteomyelitis from other etiologies. Once an initial proper diagnosis was performed, the treatment relies on the prompt initiation of appropriate pharmacotherapy and serial monitoring of the clinical progress. This paper report late-onset CVO in two young patients who underwent a heart transplant surgery and had postoperative systemic candidiasis. These two cases are a good reminder of the potential of CVO in immunosuppressive patients treated with anti-fungal agents. This paper presents these two cases with a review of the relevant literature.
