A case of CMV-induced gastric ulcer.
- Author:
Mi Jeong LEE
1
;
Jae Myung PARK
;
Yoo Kyung CHO
;
In Seok LEE
;
Sang Woo KIM
;
Myung Gyu CHOI
;
In Sik CHUNG
Author Information
1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. parkjerry@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Cytomegalovirus;
Gastric ulcer;
Immunosuppression;
Stricture
- MeSH:
Biopsy;
Breast Neoplasms;
Constriction, Pathologic;
Cytomegalovirus;
Endoscopes;
Endoscopy, Gastrointestinal;
Female;
Ganciclovir;
Gastrectomy;
Humans;
Hypertrophy;
Immunochemistry;
Immunosuppression;
Middle Aged;
Pyloric Antrum;
Pylorus;
Stents;
Stomach Ulcer;
Ulcer
- From:Korean Journal of Medicine
2009;76(2):209-214
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 59-year-old female with breast cancer, who had been treated with cancer chemotherapy and radiotherapy, visited the hospital with a 2-week history of epigastric pain. Upper gastrointestinal endoscopy showed multiple ulcers with gastric hypertrophy. In the biopsy specimen, no malignant cells were observed, but some cells were positive on immunochemistry examination for cytomegalovirus (CMV). Ganciclovir was administered for 2 weeks. Her symptoms improved and the immunochemistry finding of a subsequent gastric mucosal specimen was negative. However, the lumen of the gastric antrum was too narrow for the endoscope to pass the pylorus easily. A gastric perforation resulted and was treated with total gastrectomy and esophagojejunostomy, while an endoscopic stent was inserted to allow oral intake. Here, we report a case of gastric ulcer resulting from CMV infection and stenosis as a complication in an immunosuppressant patient.
