Prebanked Autologous Transfusion using Recombinant Human Erythropoietin: Report of one case
10.4055/jkoa.1995.30.5.1232
- Author:
Won Jong BAHK
;
Jong Min SOHN
;
Ju Hai CHANG
;
Seong Keun LEE
- Publication Type:Case Report
- Keywords:
Prebanked autologous transfusion;
Recombinant human erythropoietin
- MeSH:
Blood Transfusion;
Communicable Diseases;
Decompression;
Erythropoiesis;
Erythropoietin;
Extremities;
Hepatitis;
Humans;
Hypersensitivity;
Joints;
Malaria;
Social Problems;
Spondylolisthesis;
Syphilis;
Transplants
- From:The Journal of the Korean Orthopaedic Association
1995;30(5):1232-1235
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In the orthopaedic field, some elective surgery such such as joint replacement, spinal surgery and limb sparing procedures for musculoskeletal tumors frequently need various amounts of blood trans- fusion. But homologous transfusion occasionally result in various side effect including allergic reaction, febrile reaction, coagulopathies due to reduced platelets and coagulating factors, graft versus host disease(GVHD) and transmission of infectious diseases such as malaria, syphilis, hepatitis and AIDS. Recently these complications especially in elective surgery might result in medicolegal and social problem. Risks of transfusion could be minimized with autologous blood. So many authors are interested in prebanked autologous transfusion in elective orthopaedic surgery to prevent these problems. But there might be need of additional homologous blood transfusion because of the time limited and low yield of autologous blood. Recombinant human erythropoietin(4-HuEPO) has been shown to increase erythropoiesis. The authors could yield 5 units during 14 days using r-HuEPO without any adverse reactions. Therefore we could performed decompression, posterolateral fusion with pedicular screw fixation in spondylolisthesis without additional homologous transfusion.
