Histologic evaluation of the regenerated bone using bone graft materials.
10.5051/jkape.2006.36.2.289
- Author:
Ho Chul RYU
1
;
Joon Bong PARK
;
Young Hyuk KWON
;
Yeek HERR
;
Jong Hyuk CHUNG
;
Seong Suk JUE
Author Information
1. Department of Periodontology, School of Dentistry, Kyung Hee University, Seoul, Korea. jbpark@khu.ac.kr
- Publication Type:Original Article
- Keywords:
Guided bone regeneration;
Titanium reinforced ePTFE membrane;
Bone graft materials
- MeSH:
Adult;
Male;
Female;
Humans;
Rabbits;
Animals
- From:The Journal of the Korean Academy of Periodontology
2006;36(2):289-303
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This study was performed to evaluate the effect of bone graft materials including demineralized freeze-dried bone, freeze-dried bone, deproteinized bovine bone on space-making capacity and bone formation in guided bone regeneration with titanium reinforced ePTFE membrane(TR-ePTFE). Adult male rabbits(mean BW 2kg) were used in this study. Intramarrow penetration defects were surgically created with round bur on calvaria of rabbits. TR-ePTFE membrane was adapted to calvarial defect and bone graft materials were placed. Animals were sacrificed at 2, 8, 12 weeks after surgery. Non-decalcified specimens were processed for histologic analysis and prepared with Villaneuva bone stain. The results of this study were as follows: 1. TR-ePTFE membrane was biocompatible and capable of maintaining the space-making. 2. Tissue integration was not good at TR-ePTFE membrane. Fixation was not enough. so, wound stabilization was not good. 3. In animals using deproteinized bovine bone, demineralized freeze-dried bone, bone formation was little. 4. In animals using freeze-dried bone, bone formation was better. Within the above results, bone formation may be inhibited when wound stabilizafion was not good.
