Effects of Colloidal Gold 198Au on Synovial Membrane of Rabbits
10.4055/jkoa.1989.24.2.607
- Author:
Sung Keun SOHN
;
Jae Do KIM
;
Woo Min JEONG
;
Jae Ik LEE
- Publication Type:Original Article
- Keywords:
Collidal gold 198Au infiltration of eosinophils;
Sclerotic changes in the subsynovium;
Fibrosis of synovial vessels
- MeSH:
Colloids;
Eosinophils;
Fibrosis;
Gold Colloid;
Humans;
Inflammation;
Injections, Intra-Articular;
Knee Joint;
Rabbits;
Radionuclide Imaging;
Synovial Membrane
- From:The Journal of the Korean Orthopaedic Association
1989;24(2):607-612
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Colloidal gold 198Au were injected into 40 knee joints of rabbits for the study of the change of synovial membrane. We verified even distribution of Colloidal gold 198Au about knee joints by use of scintigraphy. After then, histopathological examinations were performed by periodic intervals. The following results are obtained form this study. l. Intra-articular injection of Colloidal gold 198Au into rabbit's knee joints resulted in a mild resctive inflammation at synovium. In was charscterized by an infiltration of eosinophils and by sclerotic changes in the subsynovium and by fibrosis of synovial vessels. 2. From this study, intra-articular injection of Colloidal gold 198Au may by benefit to treat the chronic synovial effusion in human.
