Clinical Analysis of Vogt- Koyanagi-Harada Disease.
- Author:
Kyung In WOO
1
;
Hum CHUNG
Author Information
1. Department of Ophthalmology, College of Medicine, Seoul National UniversIty, Korea.
- Publication Type:Original Article
- Keywords:
Electroretinogram;
Electro-oculogram;
Visual acuity;
Vogt-Koyanagi-Harada disease
- MeSH:
Alopecia;
Female;
Headache;
Humans;
Inflammation;
Male;
Prognosis;
Seoul;
Tinnitus;
Uveomeningoencephalitic Syndrome;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
1993;34(1):26-34
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clinical records of 41 patients with Vogt-Koyanagi-Harada disease (VKH disease) who had visited Seoul National University Hospital from 1986 to 1990 were reviewed. Twenty one patients were men and twenty patients were women. Extraocular manifestations included headache (64%), alopecia (34%), poliosis (24%), vitligo (12%), tinnitus (14%), and dysacousia (14%). Arden ratios in electro-oculogram (EOG) were low in the early stages of disease, and became improved with regaining vision. The amplitudes of electroretinogram (ERG), which were low in the early stage, recovered during medication in many cases. Visual prognosis was better if patients were treated with systemic steroid from the beginning. Factors contributing to recurrent or persistent inflammation despite of treatment included numerous extraocular manifestations and delayed treatment.
