Clinical Observations on the bone Tumors
10.4055/jkoa.1977.12.4.601
- Author:
Kwon Jae ROH
;
Nam Hyun KIM
;
In Hee CHUNG
;
Jung Soon SHIN
- Publication Type:Original Article
- MeSH:
Bone Cysts;
Breast;
Cartilage;
Chondroma;
Chondrosarcoma;
Exostoses, Multiple Hereditary;
Female;
Femur;
Fibroma;
Genitalia;
Giant Cell Tumors;
Giant Cells;
Hand;
Humans;
Humerus;
Incidence;
Knee;
Knee Joint;
Liver;
Lung;
Lymphoma, Non-Hodgkin;
Male;
Multiple Myeloma;
Osteochondroma;
Osteosarcoma;
Pelvis;
Radius;
Reticulum;
Ribs;
Sex Distribution;
Skull;
Spine;
Stomach;
Tibia
- From:The Journal of the Korean Orthopaedic Association
1977;12(4):601-618
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A total of 420 cases of tumors of bone and cartilage were seen and treated at our department during the 19 years period from January, 1957 to November, 1975, This studies reviewed and analysed clinically, radiologically and pathologically. One hundred fifty-three cases (36.4%) were benign tumors. These included osteochondroma-54 cases (35.3%), benign giant cell tumor-18 cases (11.8%), enchondroma and osteoma-15 cases (9.8%) each, fibrous dysplasia-14 cases (9.2%), solitary bone cyst-13 cases (8.5%), osteoid osteoma-11 cases (7.2%),aneurysmal bone cyst and non-ossifying fibroma-5 cases (3.2%) each, chondroblastoma-2 cases (1.3%), and chondromyxoid fibroma 1 case (0.6%). Two hundred sixty-seven cases (63.6%) were malignant tumors. Among these cases, one hundred forty-nine cases (55. 9%) were metastatic bone tumors and one hundred eighteen were primary malignant bone tumors. The latter included osteogenic sarcoma 54 cases (46.0%), chondrosarcoma-19 cases (16.1%), reticulum cell sarcoma-9 cases (7.6%), multiple myeloma and malignant giant cell tumor-8 cases (6.7%) each, Ewings sarcoma-7 cases (6.0%), fibrosarcoma-5 cases (4.2%), juxtacortical osteogenic sarcoma and liposarcoma-3 cases (2.5%) each, and lymphosarcoma 2 cases (1.7%). a greated incidence of malignant tumors. The result led us to conclude that; 1. In this study of bone tumors, the ratio between benign and malignant tumors was around 1: 1. 7, a greater incidence of malignant tumors. 2. Osteochondroma was the most frequently encountered benign bone tumor (35.3%), and followed by benign giant cell tumor (11.8%). 3. Excluding metastatic bone tumor, osteogenic sarcoma was the most frequently encountered malignant bone tumor (46.0%), and followed by chondrosarcoma (16.1%). 4. The most common site of solitary osteochondroma was around knee joint including the distal femur and the proximal tibia in 15 cases (45.5%). The peak age incidence was in the second decade of life and 43 cases were solitary and 11 cases were multiple lesion. 5. In 15 cases of enchondroma, 10 cases were solitary and 5 cases were multiple lesions. The common site was phalanges of the hand. 6. Giant cell tumor was 26 eases and to be divided into pathologically Grade I & II 18 cases (69%) and Grade III 8 cases (31%). 7. The average age of giant cell tumor was 33.8 years with the peak incidence in the third and forth decade of life. 8. The common sites of giant cell tunior were the distal femur in 8 cases and proximal tibial in 4 cases and distal radius in 6 cases. More than half of these series, the tumor occurred around the knee. 9. The sex distribution of chondrosarcoma showed 4 times of the male predominence. The 2 cases of secondary chondrosarcoma arose from osteochondroma and multiple osteochondromatosis. 10. The average age of osteogenic sarcoma was 25. 5 years with the peak incidence in the second decade of life. 11. The sex distribution of osteogenic sarcoma 42 males (77.8%) and 12 females (22.2%), a male predominance. 12. The common sites of osteogenic sarcoma were distal femur and the proximal tibia and proximal humerus in 42 cases (77.8%). 13. In metastatic bone tumor, male was predominent; 90 males (60.4%) and 59 females (39.6%), and common primary site of cancer included stomach (13.4%), lung (12.8%), breast (6.0%), liver (4.7%) and female genital organ (4.7%). 14. The most common sites of metastatic tumor to bone was spine in 46.3%, and followed by pelvis, ribs, femur and skull.
