Clinical Study of Steroid Induced Side Effects in Orthopedic Field
10.4055/jkoa.1972.7.4.405
- Author:
Dae Kyung BAE
;
Han Koo LEE
- Publication Type:Original Article
- MeSH:
Adrenal Insufficiency;
Arthralgia;
Arthritis;
Arthritis, Rheumatoid;
Blood Pressure;
Clinical Study;
Dexamethasone;
Edema;
Femur Neck;
Fractures, Compression;
Fractures, Stress;
Humans;
Incidence;
Knee Joint;
Low Back Pain;
Moon;
Necrosis;
Obesity;
Orthopedics;
Osteoarthritis;
Osteoporosis;
Prednisolone;
Prescriptions;
Sepsis;
Sex Ratio;
Ulcer
- From:The Journal of the Korean Orthopaedic Association
1972;7(4):405-411
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clinical study of 40 cases who have used steroid preparations was done during past 6 months from March 72 to September 72. 1. The youngest patient was twenty, the oldest seventy-four and the average fifty-two. Eighty percent was included between from 41 to 70 year of age. 2. And the sex ratio was 1:4.7. 3. Diagnostic incidence was 47.5% in degenerative arthritis and 40% in rheumatoid arthritis. 4. The causes of administration were multiple joint pain (35%), lumbago (27.5%) and pain on knee joint (25%) in order. 5. Prednisolone (60%), dexacortisil (25%) and dexamethasone (12.5%) were used in 97.5%. 6. The source of steroid was drung store (95%) or doctor (5%). 7. The time from first dose to last dose was less than 1month (20%), 1–3 month(10%), 4–6 month (7.5%) and more than 1 year (52.5%). And 3 cases have used for more than 5 years, 8. Eighteen cases (45%) used steroid continuously and 22 cases (55%) irregularly. 9. Transient effectiveness was experienced in 92.5% with steroid administration, that was one of the causes of steroid usage without doctor's prescription. 10. The side effects were as follows; moon face (62.5%), ulcer (20%), fat deposition (15%), osteoporosis (15%), peripheral edema (10%), elevation of blood pressure (7.5%), malar flush(7.5%), vertebral compression fracture (7.5%), obesity (5%), psychotic change (5%), pyogenic arthritis (5%), diabetes (2.5%), sepsis (2.5%), adrenal insufficiency (2.5%), avascular necrosis (2.5%) and stress fracture of femur neck (2.5%).
