A Case of Severe Hypersensitivity Reaction to Para-Amino Salicyic Acid
10.4055/jkoa.1972.7.4.481
- Author:
Jung Sup EUM
;
Soo Young LEE
;
Joo Choul IHIN
;
Ik Dong KIM
- Publication Type:Case Report
- MeSH:
Aminosalicylic Acid;
Hypersensitivity;
Liver Failure, Acute;
Liver Function Tests
- From:The Journal of the Korean Orthopaedic Association
1972;7(4):481-484
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hypersensitivity reactions against para-aminos alicylic have been recorded infrequently in the literature. It is the purpose of this report to emphasize the possible occurence of severe reactions which may result in death if unrecognized. The recognition of the early signs and symptoms of a hypersensitivity reaction to antituberculous drugs is all important because serious consequences can ensue from continued administration of the drug after the first sign of a reaction. This case present acute liver failure as part of a generalized hypersensititivity reaction to para-aminosalicylic acid, based on clinical findings liver function test, course and response to cortison derivatives.