Hand-Schuller-Christian Disease
10.4055/jkoa.1971.6.3.283
- Author:
Hyun Suk KIM
;
Seung Ho YUNE
- Publication Type:Case Report
- MeSH:
Anemia;
Anti-Bacterial Agents;
Diagnosis;
Eosinophilic Granuloma;
Female;
Fever;
Hepatomegaly;
Histiocytosis, Langerhans-Cell;
Humans;
Nervous System
- From:The Journal of the Korean Orthopaedic Association
1971;6(3):283-289
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In 1953, Lichtenstein suggested to use “Histiocytosis X” as an unifying diagnostic term to represent Eosinophilic granuloma, Hand-Schiiller-Christian disease, and Letterer-Siwe disease. The author experienced a case of Hand-Schuller-Christian disease in six year old girl. She has been treated under the diagnosis of Calves disease. But later, it was confirmed as Hand-Schiiller-Christian disease by clinically and pathologically, involving multiple region of entire skeletal system, but sparing the musculocutaneous and nervous system. Clinically, anemia, malaise, high fever and hepatomegaly were present. Co60 isotope irradiation combined with antibiotics was done for 87 days twice weekly in a dose of 50 R at a time. At the time of discharge clinical symptoms were subsided. In X-Ray check, one year after treatment, bony defects were consolidated with new bone and the result was successful.
