Optic Neuritis Accompanied by Optic Perineuritis after Peribulbar Retinalamin Injection
10.3341/jkos.2019.60.6.600
- Author:
Gyeong Min LEE
1
;
Seung Joo HA
Author Information
1. Department of Ophthalmology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea. sjha@schmc.ac.kr
- Publication Type:Case Report
- Keywords:
Donut sign;
Optic neuritis;
Optic perineuritis;
Retinalamin;
Tram track sign
- MeSH:
Brain;
Diagnosis;
Female;
Fluorescein Angiography;
Headache;
Humans;
Hypersensitivity;
Kazakhstan;
Magnetic Resonance Imaging;
Middle Aged;
Optic Nerve;
Optic Neuritis;
Pupil Disorders;
Reflex;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2019;60(6):600-605
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case of optic neuritis accompanied by optic perineuritis after retinalamin peribulbar injection. CASE SUMMARY: A 46-year-old Kazakhstan woman presented with sudden vision loss, headache, and pain in both eyes which began 2 hours after the peribulbar injection of retinalamin approximately 10 days prior to her initial visit. At the initial visit, the best-corrected visual acuity was light perception in both eyes. A fundus examination showed bilateral optic disc swelling and fluorescein angiography showed late-phase leakage around the optic nerve and optic nerve sheath enhancement. On brain magnetic resonance imaging, the tram track sign and donut sign were seen in both eyes. Steroid pulse therapy was started after the diagnosis of optic neuritis accompanied by optic perineuritis. After 6 months, the patient's visual acuity improved up to 0.8 in the right eye and 1.0 in the left eye. The light reflex was recovered, the relative afferent pupillary defect decreased, and there was no evidence of optic disc swelling. CONCLUSIONS: When an unverified drug injection is performed (e.g., retinalamin), it could result in complications such as optic neuritis and optic perineuritis from an allergic reaction or peribulbar injection trauma. In such cases, high-dose steroid pulse therapy may be considered.
