Infectious Crystalline Keratopathy Caused by Alternaria
10.3341/jkos.2019.60.11.1112
- Author:
Hye Jin HONG
1
;
Jong Myoung YUN
;
Dae Jin PARK
Author Information
1. Department of Ophthalmology, Daegu Fatima Hospital, Daegu, Korea. dj_oph_2540@hanmail.net
- Publication Type:Case Report
- Keywords:
Alternaria spp.;
Corneal trauma;
Infectious crystalline keratopathy
- MeSH:
Aged;
Agriculture;
Alternaria;
Biopsy;
Corneal Injuries;
Corneal Opacity;
Corneal Stroma;
Crystallins;
Foreign Bodies;
Fungi;
Humans;
Inflammation;
Male;
Republic of Korea;
Voriconazole
- From:Journal of the Korean Ophthalmological Society
2019;60(11):1112-1116
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case of infectious crystalline keratopathy caused by Alternaria in the corneal center. CASE SUMMARY: A 66-year-old male visited our clinic with right ocular pain and visual loss after corneal trauma caused by a foreign body hitting his right eye while performing farm work 1 month prior to his visit. The patient had no history of corneal surgery and long-term use of topical corticosteroid. A corneal epithelial defect and whitish snowflake margin infiltration around the corneal stroma were observed in the corneal center, but there was an absence of conjunctival injection and anterior segment inflammation. Cultures and a biopsy of the corneal scrapings revealed Alternaria species fungus. The patient was treated with 1% topical voriconazole and 0.5% moxifloxacin, together with oral voriconazole (400 mg/day). After 2 months of treatment, the disease was completely cured, with a minute corneal opacity. CONCLUSIONS: We successfully treated a rare case of infectious crystalline keratopathy caused by Alternaria, which has not been previously reported in the Republic of Korea.
