Small Fiber Neuropathy and Postural Orthostatic Tachycardia Syndrome after Human Papillomavirus Vaccination

Author: Chaewon LEE ¹ ; Young Min LIM ; Myung A KO ; Hyunjin KIM ; Kwang Kuk KIM
Author Information

1. Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. kkkim@amc.seoul.kr
Publication Type:Case Report
Keywords: Papillomavirus vaccines; Small fiber neuropathy; Postural orthostatic tachycardia syndrome
MeSH: Adult; Erythromelalgia; Fatigue; Female; Foot; Humans; Korea; Papillomavirus Vaccines; Paresthesia; Postural Orthostatic Tachycardia Syndrome; Vaccination
From:Journal of the Korean Neurological Association 2018;36(4):318-321
CountryRepublic of Korea
Language:Korean
Abstract: We describe a 44-year-old woman with paresthesia, fatigue, and palpitation, 10 days after human papillomavirus (HPV) vaccination. The quantitative sensory test showed abnormal detection threshold in her foot. Tilt test result indicated postural orthostatic tachycardia syndrome. Symptoms were improved after immunomodulating therapy, pain control drug, and oral beta blocker medication. This is first case report for small fiber neuropathy and autonomic dysfunction after HPV vaccination in Korea.