Rituximab Treatment for Polyneuropathy Induced by an Immune Checkpoint Inhibitor
- Author:
Hye Rim SHIN
1
;
Dong Wan KANG
;
Eun Young KIM
;
Tae Min KIM
;
Soon Tae LEE
Author Information
- Publication Type:Case Report
- Keywords: Autoimmune diseases; Polyneuropathies; Rituximab
- MeSH: Autoimmune Diseases; Immunoglobulins; Neural Conduction; Polyneuropathies; Rituximab
- From:Journal of the Korean Neurological Association 2018;36(4):329-332
- CountryRepublic of Korea
- Language:Korean
- Abstract: Immune checkpoint inhibitor is associated with variety of immune-related adverse events. We present a case of polyneuropathy induced by immune checkpoint inhibitor, which was refractory to steroid and immunoglobulin. While high-dose steroid and immunoglobulin were not effective, we tried rituximab which is effective in other immune-mediated polyneuropathy. After rituximab treatment, patient's clinical symptom and nerve conduction study finding was markedly improved. We suggest rituximab might be effective in polyneuropathy induced by immune checkpoint inhibitor.
