Steroid Non-responsive Hashimoto's Encephalopathy Improved by Rituximab
- Author:
Seong Hwa JANG
1
;
Hye Jin MOON
;
Yong Won CHO
Author Information
- Publication Type:Case Report
- Keywords: Encephalopathy; Thyroid hormones; Rituximab; Glucocorticoids
- MeSH: Adrenal Cortex Hormones; Antibodies; Autoimmune Diseases; Brain Diseases; Catatonia; Female; Glucocorticoids; Humans; Immunoglobulins; Immunomodulation; Middle Aged; Rituximab; Thyroid Hormones
- From:Journal of the Korean Neurological Association 2018;36(1):19-21
- CountryRepublic of Korea
- Language:Korean
- Abstract: Hashimoto's encephalopathy is a rare autoimmune disease, with symptoms of encephalopathy and high titers of serum anti-thyroid antibodies. Current diagnostic criteria include corticosteroid responsiveness, but in some cases, they are refractory to corticosteroids. In steroid non-responders, other immunomodulatory therapies could be applied. Recently, Rituximab is reported as a safe and effective treatment for Hashimoto's encephalopathy. We report a 50-year-old woman with Hashimoto's encephalopathy presented with confusion and catatonia who was refractory to corticosteroid and immunoglobulin but effectively treated with rituximab.
