Reduction in post extraction waiting period for dental implant patients using plasma rich in growth factors: an in vivo study using cone-beam computed tomography
10.5125/jkaoms.2019.45.5.285
- Author:
Varun ARYA
1
;
Vijay Laxmy MALHOTRA
;
JK Dayashankara RAO
;
Shruti KIRTI
;
Siddharth MALHOTRA
;
Radhey Shyam SHARMA
Author Information
1. Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, SGT University, Gurgaon, India.
- Publication Type:Original Article
- Keywords:
Plasma rich in growth factors;
Bone regeneration/repair in fresh extraction sockets;
Cone-beam computed tomography;
Quality and quantity of bone;
Platelet rich plasma
- MeSH:
Bone Density;
Bone Regeneration;
Centrifugation;
Cone-Beam Computed Tomography;
Dental Implants;
Fibrin;
Humans;
Intercellular Signaling Peptides and Proteins;
Plasma;
Platelet-Rich Plasma
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2019;45(5):285-293
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: This study examined the effects of plasma-rich growth factors (PRGF) on accelerating bone regeneration/repair in fresh extraction sockets, and determined the quality and quantity of bone by assessing the bone density using cone-beam computed tomography (CBCT). MATERIALS AND METHODS: Twenty patients, who had undergone bilateral extractions, were included in this study. In one extraction socket, PRGF was used and covered with an autologous fibrin plug. Nothing was used in the opposite side extraction socket. Thirteen weeks post extraction, the level of bone regeneration was evaluated on both sides with CBCT. RESULTS: At the end of the study, the mean bone density according to the Hounsfield units (HU) in the control group and PRGF group was 500.05 HU (type III bone type) and 647.95 HU (type II bone type), respectively. CONCLUSION: This study recommends the use of PRGF in post extraction sites to accelerate the rate of bone regeneration and improve the quality of regenerated bone. The technique to process PRGF was simple compared to previously mentioned techniques used for platelet-rich plasma (PRP) preparation. PRP preparation requires a two-cycle centrifugation procedure, leading to a longer processing time.
