Influence of wound closure on volume stability with the application of different GBR materials: an in vitro cone-beam computed tomographic study
10.5051/jpis.2019.49.1.14
- Author:
Nadja NAENNI
1
;
Tanja BERNER
;
Tobias WALLER
;
Juerg HUESLER
;
Christoph Hans Franz HÄMMERLE
;
Daniel Stefan THOMA
Author Information
1. Clinic of Fixed and Removable Prosthodontics and Dental Material Science, Center of Dental Medicine, University of Zurich, Zurich, Switzerland. nadja.naenni@zzm.uzh.ch
- Publication Type:Original Article
- Keywords:
Alveolar ridge augmentation;
Bone regeneration;
Bone substitute;
Cone-beam computed tomography;
In vitro;
Membranes
- MeSH:
Alveolar Ridge Augmentation;
Bone Regeneration;
Bone Substitutes;
Collagen;
Cone-Beam Computed Tomography;
In Vitro Techniques;
Mandible;
Membranes;
Shoulder;
Wounds and Injuries
- From:Journal of Periodontal & Implant Science
2019;49(1):14-24
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To assess the influence of using different combinations of guided bone regeneration (GBR) materials on volume changes after wound closure at peri-implant dehiscence defects. METHODS: In 5 pig mandibles, standardized bone defects were created and implants were centrally placed. The defects were augmented using different combinations of GBR materials: xenogeneic granulate and collagen membrane (group 1, n=10), xenogeneic granulate and alloplastic membrane (group 2, n=10), alloplastic granulates and alloplastic membrane (group 3, n=10). The horizontal thickness was assessed using cone-beam computed tomography before and after suturing. Measurements were performed at the implant shoulder (HT0) and at 1 mm (HT1) and 2 mm (HT2) below. The data were statistically analysed using the Wilcoxon signed-rank test to evaluate within-group differences. Bonferroni correction was applied when calculating statistical significance between the groups. RESULTS: The mean horizontal thickness before suturing was 2.55±0.53 mm (group 1), 1.94±0.56 mm (group 2), and 2.49±0.73 mm (group 3). Post-suturing, the values were 1.47±0.31 mm (group 1), 1.77±0.27 mm (group 2), and 2.00±0.48 mm (group 3). All groups demonstrated a loss of horizontal dimension. Intragroup changes exhibited significant differences in group 1 (P < 0.001) and group 3 (P < 0.01). Intergroup comparisons revealed statistically significant differences of the relative changes between groups 1 and 2 (P=0.033) and groups 1 and 3 (P=0.015). CONCLUSIONS: Volume change after wound closure was minimized by using an alloplastic membrane. The stability of the augmented horizontal thickness was most ensured by using this type of membrane irrespective of the bone substitute material used for membrane support.
