Association of chairside salivary aMMP-8 findings with periodontal risk assessment parameters in patients receiving supportive periodontal therapy
10.5051/jpis.2018.48.4.251
- Author:
Gerhard SCHMALZ
1
;
Max Kristian KUMMER
;
Tanja KOTTMANN
;
Sven RINKE
;
Rainer HAAK
;
Felix KRAUSE
;
Jana SCHMIDT
;
Dirk ZIEBOLZ
Author Information
1. Department of Cariology, Endodontology and Periodontology, University Leipzig, Leipzig, Germany. dirk.ziebolz@medizin.uni-leipzig.de
- Publication Type:Original Article
- Keywords:
Maintenance;
Metalloproteinase (aMMP-8);
Periodontitis;
Risk assessment;
Supportive periodontal therapy
- MeSH:
Chronic Periodontitis;
Cross-Sectional Studies;
Diagnosis;
Hemorrhage;
Humans;
Oral Hygiene Index;
Periodontitis;
Retrospective Studies;
Risk Assessment;
Smoke;
Smoking;
Tooth
- From:Journal of Periodontal & Implant Science
2018;48(4):251-260
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The aim of this retrospective cross-sectional study was to evaluate whether salivary findings of active matrix-metalloproteinase 8 (aMMP-8) chairside (point of care; POC) tests were associated with periodontal risk assessment parameters in patients receiving supportive periodontal therapy (SPT). METHODS: A total of 125 patients receiving regular SPT were included, and their records were examined. The following inclusion criteria were used: a diagnosis of chronic periodontitis, at least 1 non-surgical periodontal treatment (scaling and root planning) with following regular SPT (minimum once a year), at least 6 remaining teeth, and clinical and aMMP-8 findings that were obtained at the same appointment. In addition to anamnestic factors (e.g., smoking and diabetes), oral hygiene indices (modified sulcus bleeding index [mSBI] and approximal plaque index), periodontal probing depth simultaneously with bleeding on probing, and dental findings (number of decayed, missing, and filled teeth) were recorded. Salivary aMMP-8 levels were tested using a commercial POC test system (Periomarker, Hager & Werken, Duisburg, Germany). Statistical analysis was performed using the t-test, Mann-Whitney U test, Fisher's exact test, and χ2 test, as appropriate (P < 0.05). RESULTS: Only the mSBI was significantly associated with positive salivary aMMP-8 findings (aMMP-8 positive: 27.8%±20.9% vs. aMMP-8 negative: 18.0%±14.5%; P = 0.017). No significant associations were found between aMMP-8 and smoking, diabetes, periodontal parameters, or parameters related to the maintenance interval (P > 0.05). CONCLUSIONS: Salivary aMMP-8 chairside findings were not associated with common parameters used for periodontal risk assessment in patients receiving SPT. The diagnostic benefit of POC salivary aMMP-8 testing in risk assessment and maintenance interval adjustment during SPT remains unclear.
