Squamous Cell Carcinoma of the Extrahepatic Common Hepatic Duct
- Author:
Myunghee KANG
1
;
Na Rae KIM
;
Dong Hae CHUNG
;
Hyun Yee CHO
;
Yeon Ho PARK
Author Information
- Publication Type:Case Report
- Keywords: Carcinoma, squamous cell; Klatskin tumor; Hepatic duct, common; Hilum; Chemotherapy
- MeSH: Adenocarcinoma; Bile Ducts, Extrahepatic; Carcinoma, Squamous Cell; Common Bile Duct; Drug Therapy; Epithelial Cells; Epithelium; Female; Hepatic Duct, Common; Humans; Keratins; Klatskin Tumor; Mastectomy, Segmental; Middle Aged; Nausea
- From:Journal of Pathology and Translational Medicine 2019;53(2):112-118
- CountryRepublic of Korea
- Language:English
- Abstract: We report a rare case of hilar squamous cell carcinoma. A 62-year-old Korean woman complaining of nausea was referred to our hospital. Her biliary computed tomography revealed a 28 mm-sized protruding solid mass in the proximal common bile duct. The patient underwent left hemihepatectomy with S1 segmentectomy and segmental excision of the common bile duct. Microscopically, the tumor was a moderately differentiated squamous cell carcinoma of the extrahepatic bile duct, without any component of adenocarcinoma or metaplastic portion in the biliary epithelium. Immunohistochemically, the tumor was positive for cytokeratin (CK) 5/6, CK19, p40, and p63. Squamous cell carcinoma of the extrahepatic bile duct is rare. To date, only 24 cases of biliary squamous cell carcinomas have been reported. Here, we provide a clinicopathologic review of previously reported extrahepatic bile duct squamous cell carcinomas.
