Glanzmann Thrombasthenia in a Korean Patient: A Postoperative Intracranial Hemorrhagic Diasthesis in a Patient with a Rupture of a Cerebral Aneurysm
- Author:
Mi Sun CHOI
1
;
Joo Hee LEE
;
Yong Cheol LIM
Author Information
- Publication Type:Case Report
- Keywords: Trombastniahe; Postoperative hemorrhages; Aneurysm, Ruptured
- MeSH: Aneurysm; Aneurysm, Ruptured; Angiography; Blood Platelets; Brain; Cerebral Hemorrhage; Diagnosis, Differential; Drainage; Female; Follow-Up Studies; Hematologic Tests; Hemorrhage; Humans; Hydrocephalus; Intracranial Aneurysm; Intracranial Hemorrhages; Middle Aged; Postoperative Hemorrhage; Rare Diseases; Rupture; Stupor; Thrombasthenia; Ventriculoperitoneal Shunt
- From: Journal of Neurocritical Care 2017;10(2):126-128
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: Glanzmann thrombasthenia (GT) is a rare disease with severe insufficiency of platelet function. There are no reports of GT associated with a cerebral hemorrhage. CASE REPORT: A 45-year-old woman had a stuporous mentality. Her computed tomographic (CT) angiography revealed a rupture of the posterior cerebral artery aneurysm. Hunt-Hess grade was 4 points and Fisher grade was 3 points. A clipping of the aneurysm was performed and proceeded to external ventricular drainage for hydrocephalus after 6 days. But, a new hemorrhage was detected several times via a follow-up brain CT. Various blood tests were conducted to evaluate the bleeding tendency, and the GT was diagnosed with PFA-200. The ventriculoperitoneal shunt was performed after the platelets transfusion, and she was discharged without other complications. CONCLUSION: With nonspecific and recurrent intracranial hemorrhage, a GT should be included in the differential diagnosis, which is important in controlling bleeding during the surgery.
