The Effect of Short-term Treatment with Fennel on Lipid Profile in Postmenopausal Women: A Randomized Controlled Trial
- Author:
Maliheh AFIAT
1
;
Elham AMINI
;
Masumeh GHAZANFARPOUR
;
Bahareh NOURI
;
Mahsa Sadat MOUSAVI
;
Masoudeh BABAKHANIAN
;
Hassan RAKHSHANDEH
Author Information
- Publication Type:Randomized Controlled Trial
- Keywords: Foeniculum; Lipids; Postmenopause
- MeSH: Cholesterol; Female; Foeniculum; Follow-Up Studies; Humans; Lipoproteins; Postmenopause; Sample Size; Triglycerides
- From:Journal of Menopausal Medicine 2018;24(1):29-33
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVES: The present trial aimed to assess the effects of Fennel (Foeniculum vulgare Mill.) on lipid profiles. METHODS: In this double blind, randomized and placebo-controlled trial, sixty eligible postmenopausal women were randomly assigned into the fennel and placebo groups. Total blood cholesterol, cholesterol fractions, and triglycerides were tested at the baseline, and after three-month follow-up. RESULTS: There was no significant difference in triglyceride (P = 0.679), total cholesterol (P = 0.103), low-density lipoprotein cholesterol (LDL-C; P = 0.146) and high-density lipoprotein cholesterol (HDL-C; P = 0.266) levels between the two groups. In addition, in both groups, a paired t.test showed no significant difference in all mentioned parameters, except for HDL-C, indicating significant borderline improvement (P = 0.052) in the fennel group. CONCLUSIONS: The fennel group revealed a very slight positive change in LDL-C, triglyceride and HDL-C. Further studies with longer durations, higher doses, and larger sample sizes are recommended to validate the results.
